Incorrect aseptic techniques in medicine preparation and recommendations for safer practices: a systematic review

Many patient deaths have been reported because of administration of contaminated intravenous medicines due to incorrect aseptic techniques. The aim was to review the literature for incorrect practices in aseptic drug preparation and administration and recommendations for safer practices in hospitals.

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A systematic literature search was conducted in PubMed covering 2007–2015. Studies were included if they concerned aseptic medicine preparation and administration in hospitals by different healthcare professionals, assessed incorrect practices and made recommendations for safer aseptic preparation and administration.

Authors: Eeva Suvikas-Peltonen, Suvi Hakoinen, Ercan Celikkayalar, Raisa Laaksonen, Marja Airaksinen

Methods A systematic literature search was conducted in PubMed covering 2007–2015. Studies were included if they concerned aseptic medicine preparation and administration in hospitals by different healthcare professionals, assessed incorrect practices and made recommendations for safer aseptic preparation and administration.

Conclusions: The review discusses many appropriate and enhanced practices in aseptic drug preparation and administration. As the change for the better in contamination rates of administered medicines seems to be challenging to achieve in hospitals, better and possibly international procedures for safe parenteral practices need to be developed

To cite: Suvikas-Peltonen E, Hakoinen S, Celikkayalar E, et al. Eur J Hosp Pharm 2017; 24:175–181.

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